Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in /home/bioout0b0iuo3opupt/wwwroot/model/module_block.php on line 4
Strict Standards: Redefining already defined constructor for class image in /home/bioout0b0iuo3opupt/wwwroot/library/image.class.php on line 20
搜索
分类
Deprecated: Non-static method ProductCategory::getCategoryArray() should not be called statically, assuming $this from incompatible context in /home/bioout0b0iuo3opupt/wwwroot/module/mod_category_p.php on line 28 Deprecated: mysql_escape_string(): This function is deprecated; use mysql_real_escape_string() instead. in /home/bioout0b0iuo3opupt/wwwroot/model/product_category.php on line 57 Strict Standards: Only variables should be assigned by reference in /home/bioout0b0iuo3opupt/wwwroot/model/product_category.php on line 108 Deprecated: mysql_escape_string(): This function is deprecated; use mysql_real_escape_string() instead. in /home/bioout0b0iuo3opupt/wwwroot/model/product_category.php on line 57 Strict Standards: Only variables should be assigned by reference in /home/bioout0b0iuo3opupt/wwwroot/model/product_category.php on line 108登录
连接
内容编辑Gsdmd敲除小鼠
分类: 免疫炎症鼠
发布时间: 2019-08-06 11:00
应用：细胞焦亡
级别：SPF
类型：KO
背景：C57BL/6
名称：Gsdmd-KO
编号：LM000207
级别：SPF
类型：KO
背景：C57BL/6
名称：Gsdmd-KO
编号：LM000207
使用基因编缉技术删除Gsdmd基因外显子，建立Gsdmd基因敲除小鼠模型。Gsdmd细胞焦亡（Pyroptosis）是由炎症小体和下游的效应因子gasdermin D（GSDMD）所介导的。在被炎性小体相关半胱天冬酶（Inflammasome-associated caspases）裂解后，GSDMD的N端结构域形成促进细胞溶解的膜孔。
| 疾病造模 | 代养代繁 | 药效评估 | 生化分析 | 行为分析 | 影像检测 | 病理检测 |